Immuno Concepts was founded in 1979 with a commitment to advance the
quality of diagnostic assays for systemic rheumatic diseases.
In 1979 Immuno Concepts pioneered the conversion from rodent tissue to
HEp-2 cells for detection of anti-nuclear antibodies (ANAs). Using genetic
engineering we developed HEp-2000, an ANA substrate with increased sensitivity
for detection of autoantibodies to SS-A/Ro. Immuno Concepts was the first
company to offer a non-fluorescent ANA. The company's Colorzyme methodology uses
a patented stabilized color reagent system that allows slide-based assays to be
read using common bright field microscopy. The Colorzyme format is available for
ANA, nDNA and EBV assays.